Enchanced Radiation Therapy Efficacy Seen

Radiation therapy  (and drugs known as radiomimetics) damages the DNA of cancer cells (normal cells too, that why targeting is important in radiation therapy).

DNA has repair mechanisms to sometimes fix the damage.

So, if one can damage the repair mechanisms of the cancerous DNA, one can improve the efficacy of the radiation therapy.

And that's what some scientists have done, using folate as a "Trojan horse" to deliver an antibody into the cell nucleus.  The antibody impairs DNA damage repair.