It's always fun to learn things are more complex than they appear.
This article describes the p53 gene which is commonly found to be mutated in cancers.
It describes a protein, NRD1, which binds with only with the mutated form, not the normal form.
We don't know why, but when NRD1 binds with mutated p53 in the presence of a particular chemical signal HB-EGF (a growth factor which plays a role in heart development & wound healing), the tumors become more invasive. And typically in tumors, there is abnormal production of HB-EGF.
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