"Enthusiasm is the yeast that rises the dough"
Paul J. Meyer
Carl Zimmer describes how our distant cousin, yeast, has been used to discover a tumor shrinking drug.
In health physics we used yeast as an aid in understanding that the genes employed to resist ionizing radiation are different than those used to resist the more common damage of metabolism called metabolic oxidative damage (MOD). This is illustrated here (where "IR" stands for ionizing radiation, and H2O2 stands for hydrogen peroxide, one of the oxidizers).
Of course this is not surprising because the type and location of IR damage is different than MOD as are the cellular repair mechanisms. This was discussed here - "DNA Damage & Repair".